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Biophysics

General data

Course ID: 1100-114BFIZ11 Erasmus code / ISCED: 13.204 / (unknown)
Course title: Biophysics Name in Polish: Biofizyka
Organizational unit: Faculty of Physics
Course groups: Requisite subjects for third-year students of Biotechnology
Course homepage: http://www.biogeo.uw.edu.pl/biofizyka_biologia
ECTS credit allocation (and other scores): 2.00
Language: Polish
Type of course:

obligatory courses

Prerequisites (description):

Dedicated to the students of the Faculty of Biology, 3rd year of study

Mode:

Classroom

Short description:

Introduction to experimental, theoretical, and methodological foundations of biophysics focused on living cells and their molecular components. Current topics of molecular biophysics according to recent publications. Selected applications of biophysics in biotechnology and medicine.

Full description:

The main aim is to present exhaustively the basis of modern molecular biophysics for the students learning biophysics at the Faculty of Biology (biotechnology). Attending the lecture should make them possible to comprehend structural and dynamical aspects of biological processes involving proteins and nucleic acids in terms of physics, and show them most important biophysical, structural methods.

Program

1. General remarks on biophysics, its history and scope. Quantum and classical description of molecules. Spectroscopic methods for studies of properties of molecules.

2. Thermodynamics and statistical physics in description of macroscopic systems with constant and variable number of chemical components. Boltzmann and Boltzmann-Gibbs laws. Kinetics of chemical reactions and other molecular processes, principle of detailed balance.

3. Biomolecules, from water to biopolymers. Review of basic properties.

4. Spectroscopic methods for studying biomplecules.

5. Microscopis methods, X-ray crystallography and NMR spectroscopy

6. Hydrodynamic methods, relaxation methods, kinetic methods

7. Computer simulation methods

8. Structure and dynamics of nucleic acids and proteins

9. Kinetics of enzymati reactions

10. Biomolecular diffusion

11. Gene expression from single molecule experiments

12. Significance of electrostatic interactions.

13. Imaging of biomolecules, their structure, dynamics and function, medical aspects.

14. Protocells and origins of life

15. Applications in biotechnology.

Student's effort:

Lecture = 30 h

Self-studying (1 h per week), ca. 15 h

Preparations to pass the examination: ca. 15 h

Total, ca. 60 h

Remarks

Presentation on transparencies available for the participants as xerox copies.

Description by Ryszard Stolarski, updated by Jan Antosiewicz, January 2019

Bibliography:

1. I. N. Serdyuk, N. R. Zaccai, J. Zaccai, Methods for molecular biophysics. Cambridge Univ. Press, Cambridge 2007 ( pdf version available on the internet)

2. T. A. Waigh, Applied Biophysics, Wiley, West Sussex, England, 2007 ( pdf version available on the internet)

Learning outcomes:

After completion the course:

KNOWLEDGE

1. The student knows the basic lows and actual, issues of modern molecular biophysics.

2. The student knows the basic experimental and theoretical methods used in molecular biophysics.

3. The student knows basic applications of biophysics in medicine.

SKILLS

1. The student is able to relate biological phenomena to their physical and chemical foundations.

2. The student is able to find a proper biophysical method to solve a biological problem.

SOCIAL ABILITIES

1. The student comprehends significance of constant study of scientific problems and methodology..

2. The student comprehends significance of physical notions and methods in bioscience.

3. The students recognizes ethical approach in scientific work.

Assessment methods and assessment criteria:

Final examination in the form of a test consisting of 15 questions with 4 proposed answers for consideration. The one correct answer for each question should be indicated.

Practical placement:

None

Classes in period "Summer semester 2020/21" (past)

Time span: 2021-02-22 - 2021-06-13
Choosen plan division:


magnify
see course schedule
Type of class: Lecture, 30 hours more information
Coordinators: Jan Antosiewicz
Group instructors: Jan Antosiewicz
Students list: (inaccessible to you)
Examination: Course - Examination
Lecture - Examination

Classes in period "Summer semester 2021/22" (future)

Time span: 2022-02-21 - 2022-06-15
Choosen plan division:


magnify
see course schedule
Type of class: Lecture, 30 hours more information
Coordinators: Jan Antosiewicz
Group instructors: Jan Antosiewicz
Students list: (inaccessible to you)
Examination: Course - Examination
Lecture - Examination
Course descriptions are protected by copyright.
Copyright by University of Warsaw.