Practical training BSc studies

The summer internship for the specialization "Molecular Biophysics" of the interdisciplinary field of "Applications of physics in biology and medicine" is aimed at deepening the students' knowledge in at least one of the fields learned during their studies, as well as familiarizing students with the specificity of working in a research laboratory.

Internships are mainly carried out in scientific institutes conducting interdisciplinary experimental research in the field of molecular biophysics, molecular biology, bioorganic chemistry, nanotechnology and related fields, as well as in pharmaceutical companies.

Classroom

Summer internships in research laboratories or pharmaceutical companies.

The aim of the classes is to familiarize the student with the specificity of work in laboratories conducting interdisciplinary research in molecular biophysics and related fields, and to deepen the student's knowledge in at least one of the fields learned during the studies.

Students can complete internships in the following institutions, among others

1. Laboratory of Biomolecular Machines, Center of New Technologies, University of Warsaw

2. Institute of Biochemistry and Biophysics of the Polish Academy of Sciences, Laboratory of Mutagenesis and DNA Reperation, Department of Biophysics and Department of Molecular Biology

3. Institute of Physical Chemistry of the Polish Academy of Sciences, Research team no. 10, Soft Matter Physicochemistry

4. Nencki Institute of Experimental Biology, Polish Academy of Sciences, Laboratory of Cell Biophysics

5. Institute of Physics of the Polish Academy of Sciences, Environmental Laboratory of Biological Physics,

6. Oncology Center - Institute, Department of Molecular Biology, Laboratory of Biochemistry

Subject:

1. Synthesis of antimicrobial nucleic acid peptides (PNA)

2. Molecular dynamics simulations using the Ficoll polymer model

3. Studies on the regulation of acetylation of human iota polymerase conducted mainly on cell lines

4. The role and interaction of AidB dehydrogenase and AlkB dioxygenase in repairing damage to DNA and RNA bases

5. Time-resolved confocal imaging of living cells

6. Investigation of diffusion of intracellular samplers using fluorescence correlation spectroscopy

7. Quantitative determination of nanoviscosity in the nuclei of human HEK 293 cells by the methods of fluorescence correlation

8. Studies of biophysics of intrinsic apoptosis - (in English only)

9. Nanoplastics in living cells

10. Assessment of lipid bilayer disruption by enveloped virus fusion peptides

11. Characteristics of the properties and interactions of proteins by methods of molecular spectroscopy

13. Purification of the human HAX1 protein in a bacterial system

Due to the large variety of internship topics, the literature will be provided individually for each topic by the internship tutor in a given institution

Knowledge:

Due to the large variety of institutions in which students undertake internships and the need for each student to choose only one of them, the knowledge obtained by the student depends significantly on the choice made. Acquiring the skills and attitudes listed below is the goal of the internship, but the specific implementation of this assumption also depends on the institution or even the group in which the internship takes place.

Skills:

1. the ability to independently plan and perform experiments in the field of molecular biophysics and related fields

2. ability to work in a team

3. ability to use research equipment used in biophysical and related research

4. the ability to develop, analyze and present experimental results

Attitudes:

1. understanding of the research ethics

2. awareness of responsibility for own results,

care for the safety of work with chemical and biological substances, as well as with the equipment used in biophysical and related research

3. camaraderie, good cooperation with other members of the research team

The basis for crediting the internship is the preparation of a correct report describing the objectives of the internship and their implementation. Due to the huge variety of possible topics, often relating to very narrow areas of knowledge or the use of sophisticated measurement methods, the report should be written in a way that allows to understand the essence of the intership and what the student has learned, for a person who is not a specialist in a given field.

prepared by Maria Agnieszka Bzowska, last modified on May 6, 2024