Auto-Oxidation and Antioxidants

General data

Course ID:	1200-1MON23OL
Erasmus code / ISCED:	13.3 Kod klasyfikacyjny przedmiotu składa się z trzech do pięciu cyfr, przy czym trzy pierwsze oznaczają klasyfikację dziedziny wg. Listy kodów dziedzin obowiązującej w programie Socrates/Erasmus, czwarta (dotąd na ogół 0) – ewentualne uszczegółowienie informacji o dyscyplinie, piąta – stopień zaawansowania przedmiotu ustalony na podstawie roku studiów, dla którego przedmiot jest przeznaczony. / (0531) Chemistry The ISCED (International Standard Classification of Education) code has been designed by UNESCO.
Course title:	Auto-Oxidation and Antioxidants
Name in Polish:	Autooksydacja i antyoksydanty
Organizational unit:	Faculty of Chemistry
Course groups:
ECTS credit allocation (and other scores):	(not available) Basic information on ECTS credits allocation principles: the annual hourly workload of the student’s work required to achieve the expected learning outcomes for a given stage is 1500-1800h, corresponding to 60 ECTS; the student’s weekly hourly workload is 45 h; 1 ECTS point corresponds to 25-30 hours of student work needed to achieve the assumed learning outcomes; weekly student workload necessary to achieve the assumed learning outcomes allows to obtain 1.5 ECTS; work required to pass the course, which has been assigned 3 ECTS, constitutes 10% of the semester student load. view allocation of credits
Language:	Polish
Type of course:	elective monographs
Short description:	During this course the students will acquire knowledge on the mechanism of lipid oxidation, free radicals and their precursors, methods of investigation of peroxidation processes, classes of substances preventing and retarding autoxidation. The students will also get the opportunity to study research literature on autoxidation chemistry
Full description:	Principles of free radical processes. Formation and detection of free radicals, their stability and reactivity. Kinetics of radical mediated processes. Chain reactions. Radicals and quasi-radicals containing oxygen. Basic lipid chemistry - role of lipids, their classification and sensitivity toward hydrogen atom abstraction processes. Structure of cell membranes and oxidative damage of lipids/phospholipid bilayers. Kinetics of autoxidation - rates of mono and polyunsaturated fatty acid oxidation. Photooxidation and enzymatic autoxidation. Preventive antioxidants - enzymes, complexing agents, singlet oxygen quenchers. Chain-breaking antioxidants and retarders. Ascorbic acid, carotenoids, tocopherols, flavonoids. Synergism in antioxidant action. Tocopherol mediated peroxidation
Bibliography:	Grzegorz Bartosz: Druga twarz tlenu, PWN, Warszawa, 2006 B. Halliwell, J. Gutteridge: Free Radicals in Biology and Medicine, 4th edition, Oxford University Press, 2007 J. Perkins: Radical Chemistry, Ellis Horwood, London, 1994 L. Packer, J. Fuchs (Eds): Vitamin E in health and disease, Marcel Dekker Inc. New York 1992 R. A. Larson: Naturally occurring antioxidants. CRC Press, Boca Raton -New York, 1997 Cadenas E., Packer L. (Eds.): Handbook of antioxidants, Marcel Dekker, New York, 1996 Afanas'ev I. B.: Superoxide ion: Chemistry and biological implications. vol. 1-II, CRC Press, Boca Raton, 1989

This course is not currently offered.

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Copyright by University of Warsaw.