Print syllabusIntroduction to Metalo-Organic Chemistry: Applications in Organic Synthesis
General data
| Course ID: | 1200-2MON31L |
| Erasmus code / ISCED: |
13.3
|
| Course title: | Introduction to Metalo-Organic Chemistry: Applications in Organic Synthesis |
| Name in Polish: | Wprowadzenie do chemii metaloorganicznej - zastosowania w syntezie organicznej |
| Organizational unit: | Faculty of Chemistry |
| Course groups: |
(in Polish) Przedmioty do wyboru w semestrze 3M (S2-PRK-CHM) (in Polish) Wykłady monograficzne w semestrze letnim (S2-CH, S2-CHS) |
| Course homepage: | http://www.karolgrela.eu/ |
| ECTS credit allocation (and other scores): |
1.50
|
| Language: | Polish |
| Type of course: | elective monographs |
| Requirements: | Organic Chemistry I 1200-1CHOR1W3 |
| Prerequisites: | Organic Chemistry II 1200-1CHO2W6 |
| Prerequisites (description): | Advanced organic chemistry, stereochemistry. |
| Mode: | Classroom |
| Short description: |
Knowledge of basic and semi-advanced topics from the area of organometallic chemistry and catalysis. |
| Full description: |
This course, entitled "Introduction to organometallic chemistry" presents a set of basic and semi-advanced topics from the area of organometallic chemistry and catalysis. Selected applications of this methodology in the synthesis of advanced natural and biologically active compounds will be indicated. During the course the basics of organometallic chemistry, such as ligands classes and the formation of organometallic compounds of alkali, alkaline earth and transition metals will be discussed. Reactivity of these compounds will be discussed, with emphasis on the applications of transition metal complexes in organic synthesis. |
| Bibliography: |
1. March's advanced organic chemistry : reactions, mechanisms, and structure / Michael B. Smith, Jerry March. New York : John Wiley, 2001. 2. Chemia organiczna : rozwiązywanie problemów / Susan McMurry ; z jęz. ang. tł. W. Boczoń, H. Koroniak, J. Milecki. Warszawa : Wydawnictwo Naukowe PWN, 2012. 3. Podstawy syntezy organicznej / Mieczysław Mąkosza, Michał Fedoryński. Warszawa : Oficyna Wydawnicza Politechniki Warszawskiej, 2018 4. Chemia metaloorganiczna : pierwiastki przejściowe / Florian Pruchnik, Warszawa : Państwowe Wydawnictwo Naukowe, 1991. 5. Kataliza homogeniczna / Florian Pruchnik., Warszawa : Wydaw. Naukowe PWN, 1993 6. Kataliza heterogeniczna : podstawy i zastosowanie / G. C. Bond ; tł. z ang. Jerzy Kuryłowicz., Warszawa : Państwowe Wydawnictwo Naukowe, 1979. |
| Learning outcomes: |
After the course student will know the following issues: - basics; bonding and structure in organometallic compounds; ligands I (ŋ1) and II (ŋn≥2). - preparation of organometallic compounds; ligands and exchange; oxidative insertion and reductive elimination; lithium, Grignard and Zinc reagents. - carbene and carbine complexes in synthesis; Fisher carbenes; cycylopropanation. - carbene and carbine complexes in synthesis; Schrock carbenes; metathesis and cycloisomerisation. - Pauson-Khand reaction Cross-coupling I (Heck I, Heck II). - Cross-coupling II (Stille, Sonogashira, Suzuki); Cross-coupling III (Negishi, Kumada, Knochel). - allylic substitution, carbonylation, Tsuji-Trost; asymetric reduction (hydrogenation) and oxidation. |
| Assessment methods and assessment criteria: |
Final written exam, not test. Make-up written exam, not test. The condition of passing the exam is obtaining at least 60% of correct answers. Attendance in the lectures is mandatory. Absence in 4 classes in semester will be accepted. |
| Practical placement: |
No. |
Classes in period "Summer semester 2023/24" (in progress)
| Time span: | 2024-02-19 - 2024-06-16 |
 
MO WYK-MON
TU W TH FR |
| Type of class: |
Monographic lecture, 15 hours, 30 places
|
|
| Coordinators: | Karol Grela | |
| Group instructors: | Karol Grela | |
| Students list: | (inaccessible to you) | |
| Examination: | Grading |
Copyright by University of Warsaw.
