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Fundamentals of Asymetric Transformations

General data

Course ID: 1200-2SPEC112M
Erasmus code / ISCED: 13.3 Kod klasyfikacyjny przedmiotu składa się z trzech do pięciu cyfr, przy czym trzy pierwsze oznaczają klasyfikację dziedziny wg. Listy kodów dziedzin obowiązującej w programie Socrates/Erasmus, czwarta (dotąd na ogół 0) – ewentualne uszczegółowienie informacji o dyscyplinie, piąta – stopień zaawansowania przedmiotu ustalony na podstawie roku studiów, dla którego przedmiot jest przeznaczony. / (0531) Chemistry The ISCED (International Standard Classification of Education) code has been designed by UNESCO.
Course title: Fundamentals of Asymetric Transformations
Name in Polish: Podstawy transformacji asymetrycznych
Organizational unit: Faculty of Chemistry
Course groups: (in Polish) Przedmioty do wyboru w semestrze 3M (S2-PRK-CHM)
(in Polish) Wykłady specjalizacyjne w semestrze 2M
ECTS credit allocation (and other scores): 3.00 Basic information on ECTS credits allocation principles:
  • the annual hourly workload of the student’s work required to achieve the expected learning outcomes for a given stage is 1500-1800h, corresponding to 60 ECTS;
  • the student’s weekly hourly workload is 45 h;
  • 1 ECTS point corresponds to 25-30 hours of student work needed to achieve the assumed learning outcomes;
  • weekly student workload necessary to achieve the assumed learning outcomes allows to obtain 1.5 ECTS;
  • work required to pass the course, which has been assigned 3 ECTS, constitutes 10% of the semester student load.
Language: Polish
Type of course:

obligatory courses
Short description:

Acquiring the knowledge of basic concepts of modern optical activation methods
Full description:

This course is designed to survey the fundamental principles of molecular asymmetry in biological and synthetic organic chemistry. Topics include properties of stereoisomers and properties of racemates and their enantiomeric components. Stereoisomers discrimination in achiral and chiral envirionment. Biodiscrimination. Enzymatic reactions. Origin of enantiomeric homogenity in nature and the origin of life. Concepts of non-conservating of parity in modern physics and its consequences in chemistry. Absolute asymmetric synthesis. Asymmetric transformations of racemates. Resolution of stereoisomers. Enantiomeric and diastereomeric enrichment and kinetic resolution. Racemization mechanisms and applications. Basic concepts of stereoselective synthesis (Hammond postulate and Curtin-Hammett principle). Models for chirality transfer. Thermodynamic and stereoelectronic effects in stereodifferentiation. Selected examples of stereoselective synthesis
Bibliography:

E.L. Eliel, S.H. Wilen, "Stereochemistry of Organic Compounds", John Wiley & Sons, New York, 1994

M. J. T. Robinson, Organic Stereochemistry, Oxford University Press, Oxford, 2000
Learning outcomes:

Good knowledge on stereoisomer recognition in modern chemistry and biochemistry.
Assessment methods and assessment criteria:

Egzamination in written or oral form.
Practical placement:

Not applicable.

Classes in period "Summer semester 2023/24" (in progress)

Time span: 2024-02-19 - 2024-06-16
Selected timetable range:
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Type of class:
Specialised lecture, 30 hours, 50 places more information
Coordinators: Zbigniew Czarnocki
Group instructors: Zbigniew Czarnocki
Students list: (inaccessible to you)
Examination: Examination
Course descriptions are protected by copyright.
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