Synthesis of Labeled Compounds and their Application in Organic Chemistry, Biochemistry and Medicine
General data
Course ID: | 1200-2SPEC132M |
Erasmus code / ISCED: |
13.3
|
Course title: | Synthesis of Labeled Compounds and their Application in Organic Chemistry, Biochemistry and Medicine |
Name in Polish: | Syntezy związków znakowanych i ich zastosowanie w chemii organicznej, biochemii i medycynie |
Organizational unit: | Faculty of Chemistry |
Course groups: |
(in Polish) Przedmioty do wyboru w semestrze 3M (S2-PRK-CHM) (in Polish) Wykłady specjalizacyjne w semestrze 2M |
ECTS credit allocation (and other scores): |
3.00
|
Language: | Polish |
Type of course: | obligatory courses |
Prerequisites (description): | The student before starting the course should: - demonstrate knowledge of the basics of knowledge in the field of organic chemistry and nuclear chemistry, - demonstrate the ability to search and use textbook literature. |
Mode: | Classroom |
Short description: |
After completing the course of this subject, students should demonstrate knowledge of: - the use of modern techniques in the synthesis of compounds labeled with stable and radioactive isotopes, - the use of these compounds as radiopharmaceuticals in medicine and positron emission tomography (PET), - research on reaction mechanisms by isotope methods. |
Full description: |
The lecture is devoted to issues related to the synthesis of labeled compounds and their application in organic chemistry, biochemistry and medicine. The lecture covers the following topics: - specific and non-specific methods for the synthesis of chemical compounds labeled with stable (2-H) and radioactive (3-H, 11-C, 14-C, 13-N, 15-O, 18-F, 76-Br, 131-I) isotopes, - radionuclides and radiopharmaceuticals used in medicine, - positron emission tomography (PET), - examination of chemical reaction mechanisms by isotope methods. |
Bibliography: |
Synthesis and Application of Isotopically Labelled Compounds, D.C. Dean, C.N.Filer, K.E. McCarthy editors, Vol.8, John Wiley and Sons, Ltd, England, 2004. |
Learning outcomes: |
After completing the course of this subject, the student should demonstrate knowledge of: - chemical, enzymatic synthesis and isotope exchange of stable and radioactive isotope compounds and the use of these compounds as radiopharmaceuticals in medicine, - positron emission tomography (PET) activities and applications in nuclear medicine, - investigation of chemical reaction mechanisms by the kinetic and solvent isotope effects method (KIE and SIE). |
Assessment methods and assessment criteria: |
Exam - test I and test II. 0% - 50% 2 51% - 60% 3 61% - 70% 3.5 71% - 80% 4 81% - 90% 4.5 91% - 100% 5 |
Practical placement: |
None. |
Classes in period "Summer semester 2023/24" (in progress)
Time span: | 2024-02-19 - 2024-06-16 |
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MO TU W TH WYK-SPE
FR |
Type of class: |
Specialised lecture, 30 hours, 30 places
|
|
Coordinators: | Elżbieta Winnicka | |
Group instructors: | Elżbieta Winnicka | |
Students list: | (inaccessible to you) | |
Examination: | Examination |
Copyright by University of Warsaw.