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Comparative genomics

General data

Course ID: 1000-719GP2
Erasmus code / ISCED: (unknown) / (unknown)
Course title: Comparative genomics
Name in Polish: Genomika porównawcza
Organizational unit: Faculty of Mathematics, Informatics, and Mechanics
Course groups: Elective courses for Computer Science
Obligatory courses for 2nd stage Bioinformatics
ECTS credit allocation (and other scores): 6.00 Basic information on ECTS credits allocation principles:
  • the annual hourly workload of the student’s work required to achieve the expected learning outcomes for a given stage is 1500-1800h, corresponding to 60 ECTS;
  • the student’s weekly hourly workload is 45 h;
  • 1 ECTS point corresponds to 25-30 hours of student work needed to achieve the assumed learning outcomes;
  • weekly student workload necessary to achieve the assumed learning outcomes allows to obtain 1.5 ECTS;
  • work required to pass the course, which has been assigned 3 ECTS, constitutes 10% of the semester student load.

view allocation of credits
Language: Polish
Type of course:

obligatory courses

Short description:

he lecture aims to familiarize students with selected models, algorithms, and tools used in comparative genomics, particularly on trees, and their application in various contexts. The planned exercises will be partly in the form of a computer laboratory.

Full description:

1. Basic notions: genes, species, genomes, evolution, multiple alignments, comparing sequences.

2. Models of sequence evolution.

3. Tree inference: maximum likelihood, maximum parsimony, neighbor-joining.

4. Bayesian methods.

5. Clustering of molecular sequences

6. Hierarchical clustering.

7. Bootstrapping.

8. Consensus trees.

9. Supertrees.

10. Reconciled trees.

11. Phylogenetic networks.

Bibliography:

1. Joseph Felsenstein, Inferring Phylogenies

2. Paul G. Higgs, Teresa K. Attwood, Bioinformatics and Molecular Evolution

3. R. Durbin, S. Eddy, A. Krogh, G. Mitchson, Biological Sequence Analysis.

Learning outcomes:

has knowledge of advanced methods used in comparative genomics

can perform calculations related to comparing genomes and interpret their results

Assessment methods and assessment criteria:

Large lab project – 33 pts. (required at least 15)

Small lab projects – up to 10 pts.

Exam - 60 pts.

Exam "0": large lab project + 50% small lab points required

Classes in period "Winter semester 2023/24" (past)

Time span: 2023-10-01 - 2024-01-28
Selected timetable range:
Navigate to timetable
Type of class:
Lab, 30 hours more information
Lecture, 30 hours more information
Coordinators: Paweł Górecki
Group instructors: Paweł Górecki
Students list: (inaccessible to you)
Examination: Examination

Classes in period "Winter semester 2024/25" (future)

Time span: 2024-10-01 - 2025-01-26
Selected timetable range:
Navigate to timetable
Type of class:
Lab, 30 hours more information
Lecture, 30 hours more information
Coordinators: Paweł Górecki
Group instructors: Paweł Górecki
Students list: (inaccessible to you)
Examination: Examination
Course descriptions are protected by copyright.
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Krakowskie Przedmieście 26/28
00-927 Warszawa
tel: +48 22 55 20 000 https://uw.edu.pl/
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