Organic Chemistry II Laboratory

obligatory courses

Organic Chemistry I 1200-1CHMCHO12

Knowledge of the basics of organic chemistry (basic course), confirmed by a passed exam in Organic Chemistry I.

Classroom

As part of this course, students should acquire the ability to work safely in an organic chemistry lab. They should know basic laboratory techniques, such as extraction, crystallization, distillation, distillation under reduced pressure, and should be able to synthesize simple organic compounds.

Students work individually. At the beginning of the course, basic laboratory techniques (crystallization, extraction, distillation) will be presented by the tutors. Then, students will repeat the introductory exercises individually. Before starting the synthetic work, the students pass the preliminary test, consisting of two parts: simple calculations (concentrations, conversion of concentrations, calculation of reaction yield, etc.) and the knowledge of basic laboratory techniques and principles of safe laboratory work. Then students conduct the synthesis of 6 organic compounds with increasing difficulty. Before starting each synthesis, students need to pass the test on theoretical knowledge about the classes of compounds to which the product and substrates belong (basic reactions and mechanisms). They also need to know the details of experimental procedure and safety precautions related to the particular synthesis.

By conducting the synthesis of simple organic compounds, students practically apply and consolidate their knowledge of organic chemistry, learn how to properly organize work in accordance with health and safety requirements, observe and control the course of the experiment and take laboratory notes in accordance with accepted standards.

At the end of the semester, students pass a final test on practical and theoretical knowledge of organic synthesis. It will be a written test.

Two excused absences are allowed, although all exercises must be completed.

Basics of organic chemistry:

1. (en) J. E. McMurry, Organic Chemistry (8th ed.), Brooks/Cole Cengage Learning, Belmont 2012 (and other editions).

2. (en) R.T. Morrison, R.N. Boyd,Organic Chemistry (6th ed.), Prentice-Hall Inc., Engelwood Cliffs 1992 (and other editions).

3. (en) J. Clayden, N. Greeves, S. Warren, P. Wothers, Organic Chemistry (2nd ed.), Oxford University Press, 2012 (and other editions).

Practical organic chemistry:

1. (pl) Misicka A., Orłowska A., Piekarska-Bartoszewicz B., Witkowska E., Podstawy preparatyki organicznej. Skrypt dla studentów II roku Wydziału Chemii UW, LIBER, Warszawa 2012 (and other editions).

2. (en) A. Vogel,Textbook of Practical Organic Chemistry (5th ed.), Longman Group UK Ltd., Harlow 1984.

3. (pl) J. Wróbel, Preparatyka i elementy syntezy organicznej, PWN, Warszawa 1983.

Upon completing the course, the student:

- knows the rules of safe work in the organic chemistry laboratory and can find information on the risks of working with specific chemicals

- can understand the given simple synthetic procedure and, on according to it, can perform required laboratory operations (set up the glassware, conduct the reaction, isolate and purify the product), and can calculate the yield of the final product,

- can propose a rational method of separating the mixture of compounds and purifying its components and practically performs simple distillation, liquid / liquid extraction, crystallization,

- understands the importance of careful planning of the experiment, observation and control of its course as well as taking the laboratory notes.

Requirements for passing the course:

1) Acceptance of the written reports on the basic laboratory techniques (crystallization, extraction, distillation)

2) Passing tests (with a mark) before each synthesis, individual performing of the reactions and approval with a mark of written reports. The final grade depends also on the yield of the reaction and overall quality of work (cleanliness and safety requirements), as well as the way of conducting laboratory notes.

3) Passing with a mark all required tests during the course:

- preliminary test consisting of two parts: calculations (percentage, molar concentration, conversion of concentrations, calculation of reaction yields, etc.) as well as OHS principles and basic laboratory techniques. Completing both parts of this test is necessary to start practical excercises. The test can be improved.

-final test on practical and theoretical knowledge about organic synthesis.

To pass tests it is required to obtain at least 60% of points (if the test consists of two parts, the student must obtain 60% of points in each part).

Conditions for passing in the correction session:

Students who did not complete all practical exercises within the deadline may do ONE exercise during the correction period. Failure to perform more than one exercise makes it impossible to pass a course.

Students who did not pass the final test may pass it in the correction session.

Not applicable