University of Warsaw - Central Authentication System

Chromatin and Epigenetics

General data

Course ID:	1400-235CHiE
Erasmus code / ISCED:	13.104 Kod klasyfikacyjny przedmiotu składa się z trzech do pięciu cyfr, przy czym trzy pierwsze oznaczają klasyfikację dziedziny wg. Listy kodów dziedzin obowiązującej w programie Socrates/Erasmus, czwarta (dotąd na ogół 0) – ewentualne uszczegółowienie informacji o dyscyplinie, piąta – stopień zaawansowania przedmiotu ustalony na podstawie roku studiów, dla którego przedmiot jest przeznaczony. / (0511) Biology The ISCED (International Standard Classification of Education) code has been designed by UNESCO.
Course title:	Chromatin and Epigenetics
Name in Polish:	Chromatyna i epigenetyka
Organizational unit:	Faculty of Biology
Course groups:	(in Polish) Przedmioty obieralne na studiach drugiego stopnia na kierunku bioinformatyka Elective subjects Facultative courses, BIOLOGY, specialization level (2nd study cycle), spec.: BM Specific programme courses of 2nd stage Bioinformatics
ECTS credit allocation (and other scores):	2.00 Basic information on ECTS credits allocation principles: the annual hourly workload of the student’s work required to achieve the expected learning outcomes for a given stage is 1500-1800h, corresponding to 60 ECTS; the student’s weekly hourly workload is 45 h; 1 ECTS point corresponds to 25-30 hours of student work needed to achieve the assumed learning outcomes; weekly student workload necessary to achieve the assumed learning outcomes allows to obtain 1.5 ECTS; work required to pass the course, which has been assigned 3 ECTS, constitutes 10% of the semester student load.
Language:	Polish
Main fields of studies for MISMaP:	biology biotechnology
Type of course:	elective monographs
Prerequisites (description):	Students should have basic knowledge about genetics and biochemistry. Completion of courses covering genetics, biochemistry, and molecular biology is recommended.
Mode:	Classroom
Short description:	Lectures present actual knowledge about chromatin biology. Among the subjects covered by the course are: chromatin structure, epigenetic modifications, chromatin-based regulatory mechanisms, cellular memory, and epigenetic inheritance.
Full description:	1. Introduction. Chromatin- structure and functions. 2,3. Histone modifications. 4. Histone variants. 5. DNA methylation. 6. Overview of methods used in chromatin biology. 7. Linker histones. 8. Nucleosomal and higher-order chromatin organization 9. Chromatin remodeling. 10. Non-coding RNAs. 11. Epigenetic gene silencing and Polycomb proteins. 12. Epigenetic regulation of animal and plant development. 13. Chromatin and cancer.
Bibliography:	1. Epigenetics. C. David Allis, Thomas Jenuwein, Danny Reinberg. CSHL Press, 2007 2. Fundamental Molecular Biology. Lizabeth A. Allison. Wiley, 2011. 3. Recent articles from scientific journals provided by lecturers.
Learning outcomes:	Students will improve their knowledge about chromatin-based mechanisms of gene regulation and epigenetic phenomena.
Assessment methods and assessment criteria:	Exam in a written form (test, close-ended questions).
Practical placement:	n/a

Classes in period "Summer semester 2023/24" (in progress)

Time span:	2024-02-19 - 2024-06-16	Selected timetable range: weekly course term Navigate to timetable MO TU W TH WYK FR
Type of class:	Lecture, 30 hours more information
Coordinators:	Rafał Archacki, Marta Koblowska
Group instructors:	Rafał Archacki, Marta Koblowska
Students list:	(inaccessible to you)
Examination:	Course - Examination Lecture - Examination

Course descriptions are protected by copyright.
Copyright by University of Warsaw.